产品名称

Dacarbazine(达卡巴嗪)

一般描述

Dacarbazine is a triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-s DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis used in the treatment of various cancers.

别 称

DTIC-Dome; 4-[(E)-dimethylaminodiazenyl]-1H-imidazole-5-carboxamide

纯 度

≥98.0%(HPLC)

CAS NO.

4342-03-4

分子式

C⁶H¹⁰N⁶O

分子量

182.187

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或微黄色固体

溶解性(25°C)

DMSO

~5mg/ml

乙醇

Very slightly soluble

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Dacarbazine is a triazene derivative with antineoplastic activity. Dacarbazine alkylates and cross-s DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov