产品名称

Altretamine(六甲蜜胺)

一般描述

Altretamine is an anti-neoplastic agent.

别 称

Hexamethylmelamine; NSC13875; ENT50852; 2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine

纯 度

≥98.0%(HPLC)

CAS NO.

645-05-6

分子式

C⁹H¹⁸N⁶

分子量

210.285

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25°C)

DMSO

~5mg/ml

乙醇

≥15mg/ml

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Altretamine is a synthetic cytotoxic s-triazine derivative similar in structure to alkylating agent triethylenemelamin with antineoplastic activity. Although the precise mechanism by which altretamine exerts its cytotoxic effect is unknown, N-demethylation of altretamine may produce reactive intermediates which covalently bind to DNA, resulting in DNA damage.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov