产品名称

Epothilone A(埃博霉素A)

一般描述

Epothilone A is a paclitaxel-like microtubule-stabilizing agent with EC0.01 of 2 μM.

纯 度

≥98.0%(HPLC)

CAS NO.

152044-53-6

分子式

C²⁶H³⁹NO⁶S

分子量

493.659

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25°C)

DMSO

≥45mg/ml

乙醇

≥45mg/ml

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Epothilone A is an epithilone that is epothilone C in which the double bond in the macrocyclic lactone ring has been oxidised to the corresponding epoxide (the13R,14S diastereoisomer). It has a role as an antineoplastic agent, a tubulin modulator, a metabolite and a microtubule-stabilising agent. It is an epoxide and an epothilone.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov