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Felbamate

商品编号: TS0565
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详细介绍

l  基本信息

产品名称

Felbamate(非氨酯)

一般描述

Felbamate is an anticonvulsant drug used in the treatment of epilepsy NMDAR antagonist.

别 称

ADD-03055; Felbatol; (3-carbamoyloxy-2-phenylpropyl) carbamate

纯 度

≥98.0%(HPLC)

CAS NO.

25451-15-4

分子式

C11H14N2O4

分子量

238.243

适用范围

生物试剂,适用于细胞培养等

l  理化信息

外 观

白色至类白色或浅米黄色固体

溶解性(25°C)

DMSO

≥25mg/mL

乙醇

Very slightly soluble

Very slightly soluble

l  生物学信息

生物活性/药理作用

Felbamate is a propanediol compound with anticonvulsant and antiepileptic properties. Although the exact mechanism of action is unknown, Felbamate may be an antagonist at the strychnine-insensitive glycine-recognition site of the N-methyl-D-aspartate (NMDA) receptor-ionophore complex, thereby blocking the effects of the excitatory amino acids, suppressing neuronal firing, and preventing seizure activity. Felbamate also has weak inhibitory effects on gamma-aminobutyric acid (GABA) receptor binding sites which may contribute to its inhibitory effect on neuronal excitatory.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov