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Drospirenone

商品编号: TS0584
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详细介绍

l  基本信息

产品名称

Drospirenone(屈螺酮)

一般描述

Drospirenone is a synthetic progestin that is an analog to spironolactone.

别 称

ZK 3059

纯 度

≥97.0%(HPLC)

CAS NO.

67392-87-4

分子式

C24H30O3

分子量

366.501

适用范围

生物试剂,适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25°C)

DMSO

≥45mg/ml

乙醇

~5mg/ml

Very slightly soluble

l  生物学信息

生物活性/药理作用

Drospirenone is a synthetic spironolactone analogue and progestin with progestational and anti-mineralocorticoid activity. Drospirenone binds to the progesterone receptor, the resulting complex becomes activated and binds to specific sites on DNA. This results in a suppression of LH activity and an inhibition of ovulation as well as an alteration in the cervical mucus and endometrium. This leads to an increased difficulty of sperm entry into the uterus and implantation. This drug is used in oral contraceptives.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov