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详细介绍
l 基本信息 |
产品名称 | Pirarubicin(吡柔比星) |
一般描述 | Pirarubicin is an anthracycline antibiotic, and also a DNA/RNA synthesis inhibitor by intercalating into DNA and interacts with topoisomerase II, used as an antineoplastic agent. |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 72496-41-4 |
分子式 | C32H37NO12 | 分子量 | 627.643 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 橙色或橙红色固体 |
溶解性(25°C) | DMSO | ≥45mg/ml |
乙醇 | Insoluble |
水 | Very slightly soluble |
l 生物学信息 |
生物活性/药理作用 | Pirarubicin is an analogue of the anthracycline antineoplastic antibiotic doxorubicin. Pirarubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin and exhibits activity against some doxorubicin-resistant cell lines. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
