产品名称

Dyphylline(二羟丙茶碱)

一般描述

Dyphylline is a xanthine derivative with bronchodilator and vasodilator effects.

别 称

Diprophylline; 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione

纯 度

≥98.0%(HPLC)

CAS NO.

479-18-5

分子式

C¹⁰H¹⁴N⁴O⁴

分子量

254.246

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25°C)

DMSO

≥35mg/ml

乙醇

Insoluble

水

≥35mg/ml

l  生物学信息

生物活性/药理作用

Dyphylline is a xanthine derivative. Dyphilline exerts bronchodilator effects and to a lesser extent vasodilator and diuretic properties. Dyphilline probably acts as a competitive inhibitor of phosphodiesterase which leads to an increase in intracellular cAMP.  This results in relaxation of bronchial smooth muscle and other smooth muscles. Dyphylline may also antagonize adenosine receptors. Dyphylline is used in the treatment of acute bronchial asthma, chronic bronchitis and emphysema.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov