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详细介绍
l 基本信息 |
产品名称 | Tazarotene |
一般描述 | Tazarotene is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin. |
别 称 | AGN190168; ethyl 6-[2-(4,4-dimethyl-2,3-dihydrothiochromen-6-yl)ethynyl]pyridine-3-carboxylate |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 118292-40-3 |
分子式 | C21H21NO2S | 分子量 | 351.464 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 固体 |
溶解性(25°C) | DMSO | ≥50mg/ml |
乙醇 | ≥50mg/ml |
水 | Very slightly soluble |
l 生物学信息 |
生物活性/药理作用 | Tazarotene is a synthetic, topical retinoid. Tazarotene induces the of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
