产品名称

Monobenzone(4-苄氧基苯酚)

一般描述

Monobenzone is a compound used as a topical agent for medical depigmentation. It can specifically block tyrosinase.

别 称

4-phenylmethoxyphenol

纯 度

≥98.0%(HPLC)

CAS NO.

103-16-2

分子式

C¹³H¹²O²

分子量

200.237

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色至浅棕色固体

溶解性(25°C)

DMSO

≥25mg/ml

乙醇

≥25mg/ml

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Monobenzone is a monobenzyl ether of hydroquinone with topical depigmentation activity. Although the exact mechanism of action of depigmentation is unknown, the metabolites of monobenzone appear to have a cytotoxic effect on melanocytes. Furthermore, the depigmentation effect might be mediated through the inhibition of tyrosinase, which is essential in the synthesis of melanin pigments, thereby causing permanent depigmentation of the skin.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov