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详细介绍
l 基本信息 |
产品名称 | Isradipine(伊拉地平) |
一般描述 | Isradipine is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure. |
别 称 | PN 200-110; 3-O-methyl 5-O-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 75695-93-1 |
分子式 | C19H21N3O5 | 分子量 | 371.393 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 黄色固体 |
溶解性(25°C) | DMSO | ≥45mg/ml |
乙醇 | ≥45mg/ml |
水 | Very slightly soluble |
l 生物学信息 |
生物活性/药理作用 | Isradipine is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calcium ion channels of coronary and peripheral vascular smooth muscle, thereby dilating coronary arteries and peripheral arterioles. This increases oxygen delivery due to an increased blood flow and reduces oxygenrequirements due to decrease in total peripheral resistance. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
