Aminoglutethimide
商品编号:
TS0685
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详细介绍
l 基本信息 |
产品名称 | Aminoglutethimide(氨鲁米特) |
一般描述 | Aminoglutethimide is an aromatase inhibitor with IC50 of 10 μM. |
别 称 | BA-16038, NSC-330915; 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 125-84-8 |
分子式 | C13H16N2O2 | 分子量 | 232.283 |
适用范围 | 生物试剂,适用于细胞培养等 |
l 理化信息 |
外 观 | 白色或微黄色固体 |
溶解性(25°C) | DMSO | ≥5mg/ml |
乙醇 | Slightly soluble |
水 | Very slightly soluble |
l 生物学信息 |
生物活性/药理作用 | Aminoglutethimide is a synthetic derivative of the sedative and anticonvulsant glutethimide with anti-steroid properties. Originally used as an anticonvulsant, aminoglutethimide also blocks adrenal steroidogenesis by inhibiting the enzymatic conversion of cholesterol to pregnenolone. In addition, this agent blocks the peripheral aromatization of androgenic precursors to estrogens. Aminoglutethimide does not suppress ovarian estrogen production. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |