产品名称

Mesna(美司那)

一般描述

Mesna, a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents.

别 称

sodium;2-sulfanylethanesulfonate

纯 度

≥98.0%(HPLC)

CAS NO.

19767-45-4

分子式

C²H⁵NaO³S²

分子量

164.169

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至黄色固体

溶解性(25°C)

DMSO

≥15mg/ml

乙醇

Insoluble

水

Slightly soluble

l  生物学信息

生物活性/药理作用

Mesna is a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents. Mesna is converted to a free thiol compound in the kidney, where it binds to and inactivates acrolein and other urotoxic metabolites of ifosfamide and cyclophosphamide, thereby reducing their toxic effects on the urinary tract during urinary excretion.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov