产品名称

Pyrazinamide

一般描述

Pyrazinamide is an agent used to treat tuberculosis.

别 称

Pyrazinoic Acid Amide; pyrazine-2-carboxamide

纯 度

≥98.0%(HPLC)

CAS NO.

98-96-4

分子式

C⁵H⁵N³O

分子量

123.115

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25°C)

DMSO

≥5mg/ml

乙醇

Very slightly soluble

水

~5mg/ml

l  生物学信息

生物活性/药理作用

Pyrazinamide is a synthetic pyrazinoic acid amide derivative with bactericidal property. Pyrazinamide is particularly active against slowly multiplying intracellular bacilli (unaffected by other drugs) by an unknown mechanism of action. Its bactericidal action is dependent upon the presence of bacterial pyrazinamidase, which removes the amide group to produce active pyrazinoic acid. Pyrazinamide is an important component of multidrug therapy for tuberculosis.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov