产品名称

Ethionamide(乙硫异烟胺)

一般描述

Ethionamide is an antibiotic used in the treatment of tuberculosis.

别 称

Bayer 5312; 2-ethylpyridine-4-carbothioamide

纯 度

≥98.0%(HPLC)

CAS NO.

536-33-4

分子式

C⁸H¹⁰N²S

分子量

166.242

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

浅黄色至黄色固体

溶解性(25°C)

DMSO

≥15mg/ml

乙醇

~5mg/ml

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Ethionamide is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of action of ethionamide is unknown, it may inhibit the synthesis of mycolic acid, a saturated fatty acid found in the bacterial cell wall, thereby inhibiting bacterial cell wall synthesis. This eventually leads to bacterial cell wall disruption and cell lysis. Ethionamide may be bacteriostatic or bactericidal in action, depending on the concentration of the drug at the site of infection and the susceptibility of the organism involved.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov