产品名称

Rifaximin(利福昔明)

一般描述

Rifaximin is a RNA synthesis inhibitor by binding the β subunit of the bacterial DNA-dependent RNA polymerase, used to treat traveler's diarrhea caused by certain bacteria.

纯 度

≥98.0%(HPLC)

CAS NO.

80621-81-4

分子式

C⁴³H⁵¹N³O¹¹

分子量

785.891

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

橙色至深橙色至红棕色至深红棕色粉末

溶解性(25°C)

DMSO

≥45mg/ml

乙醇

Very slightly soluble

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting bacterial RNA synthesis and bacterial cell growth. As rifaximin is not well absorbed, its antibacterial activity is largely localized to the gastrointestinal tract.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov