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详细介绍
l 基本信息 |
产品名称 | Lomustine(洛莫司汀) |
一般描述 | Lomustine inhibits cancer cells by damaging the DNA and stops cells from dividing. |
别 称 | NSC79037; 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 13010-47-4 |
分子式 | C9H16ClN3O2 | 分子量 | 233.696 |
适用范围 | 生物试剂,适用于细胞培养等 |
l 理化信息 |
外 观 | 固体 |
溶解性(25°C) | DMSO | ≥25mg/ml |
乙醇 | ≥25mg/ml |
水 | Very slightly soluble |
l 生物学信息 |
生物活性/药理作用 | Lomustine is a nitrosourea with antineoplastic activity. Lomustine alkylates and crosss DNA, thereby inhibiting DNA and RNA synthesis. This agent also carbamoylates DNA and proteins, resulting in inhibition of DNA and RNA synthesis and disruption of RNA processing. Lomustine is lipophilic and crosses the blood-brain barrier. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |