产品名称

Etidronic acid(依替膦酸)

一般描述

Etidronic acid is a non-aminobisphosphonate, show protein tyrosine phosphatase (PTP) inhibitory activity, used for the treatment of Paget's disease and the prevention of heterotopic ossification.

别 称

(1-hydroxy-1-phosphonoethyl)phosphonic acid

含 量

60% aqueous solution;

55.0 - 65.0%(Titroation by NaOH)

CAS NO.

2809-21-4

分子式

C²H⁸O⁷P²

分子量

206.027

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

无水至浅黄色液体

l  生物学信息

生物活性/药理作用

As a member of the family of drugs known as bisphosphonates, etidronate differs from endogenous pyrophosphate in its resistance to enzymatic hydrolysis. This agent adsorbs to hydroxyapatite cells and reduces the number of osteoclasts, thereby inhibiting abnormal bone resorption. Etidronate may also directly stimulate bone formation by osteoblasts.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov