Diclofenac Sodium
商品编号:
TS0768
备注:
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详细介绍
l 基本信息 |
产品名称 | Diclofenac Sodium(双氯芬酸钠) |
一般描述 | Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 0.5 μg/ml and 0.5 μg/ml for COX-1 and -2 in intact cells, respectively, used as a nonsteroidal anti-inflammatory drug (NSAID) to relieve pain and reduce swelling in flammation. |
别 称 | GP 45840; sodium;2-[2-(2,6-dichloroanilino)phenyl]acetate |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 15307-79-6 |
分子式 | C14H10Cl2NNaO2 | 分子量 | 318.129 |
适用范围 | 生物试剂,适用于细胞培养等 |
l 理化信息 |
外 观 | 白色或微黄色固体 |
溶解性(25°C) | DMSO | ≥45mg/ml |
乙醇 | ≥45mg/ml |
水 | ~5mg/ml |
l 生物学信息 |
生物活性/药理作用 | Diclofenac Sodium is the sodium salt form of diclofenac, a benzene acetic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory activity. Diclofenac sodium is a non-selective reversible and competitive inhibitor of cyclooxygenase (COX), subsequently blocking the conversion of arachidonic acid into prostaglandin precursors. This leads to an inhibition of the formation of prostaglandins that are involved in pain, inflammation and fever. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |