产品名称

Sulfisoxazole(磺胺异恶唑)

一般描述

Sulfisoxazole is a sulfonamide antibacterial with an oxazole substituent.

别 称

NU-445; 4-amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide

纯 度

≥98.0%(HPLC)

CAS NO.

127-69-5

分子式

C¹¹H¹³N³O³S

分子量

267.303

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25°C)

DMSO

≥35mg/ml

乙醇

Very slightly soluble

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Sulfisoxazole is a broad-spectrum, short-acting sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfisoxazole competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov