产品名称

Rimantadine(金刚乙胺)

一般描述

Rimantadine is an anti-influenza virus drug for T. brucei with IC50 of 7 μM.

别 称

1-(1-adamantyl)ethanamine; Flumadine

纯 度

≥98.0%(HPLC)

CAS NO.

13392-28-4

分子式

C¹²H²¹N

分子量

179.307

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25°C)

DMSO

≥15mg/ml

乙醇

≥15mg/ml

水

≥15mg/ml

l  生物学信息

生物活性/药理作用

Rimantadine is a cyclic amine and alpha-methyl derivative of amantadine with antiviral activity. Although the exact mechanism of action of rimantadine is not understood, this agent appears to exert its antiviral effect against influenza A virus by interfering with the function of the transmembrane domain of the viral M2 protein, thereby preventing the uncoating of the virus and subsequent release of infectious viral nucleic acids into the cytoplasm of infected cells.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov