产品名称

Lacidipine(拉西地平)

一般描述

Lacidipine is a L-type calcium channel blocker, used for treating high blood pressure.

别 称

GX-1048,GR-43659X,SN-305

纯 度

≥98.0%(HPLC)

CAS NO.

103890-78-4

分子式

C²⁶H³³NO⁶

分子量

455.551

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至米白色粉末

溶解性(25°C)

DMSO

≥50mg/mL

乙醇

≥15mg/mL

水

Insoluble

l  生物学信息

生物活性/药理作用

acidipine is a specific and potent calcium antagonist with a predominant selectivity for calcium channels in the vascular smooth muscle. Its main action is to dilate predominantly peripheral and coronary arteries, reducing peripheral vascular resistance and lowering blood pressure. Following the oral administration of 4 mg lacidipine to volunteer subjects, a minimal prolongation of QTc interval has been observed (mean QTcF increase between 3.44 and 9.60 ms in young and elderly volunteers).

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov