产品名称

Chlormezanone(氯美扎酮)

一般描述

Chlormezanone a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.

别 称

2-(4-chlorophenyl)-3-methyl-1,1-dioxo-1,3-thiazinan-4-one

纯 度

≥98.0%(HPLC)

CAS NO.

80-77-3

分子式

C¹¹H¹²ClNO³S

分子量

273.731

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25°C)

DMSO

≥45mg/mL

乙醇

≥15mg/mL

水

Insoluble

l  生物学信息

生物活性/药理作用

Chlormezanone is a 1,3-thiazine that is 1,3-thiazinan-4-one S,S-dioxide in which a hydrogen at position 2 is substituted by a 4-chlorophenyl group and the hydrogen attached to the nitrogen is substituted by methyl. A non-benzodiazepine muscle relaxant, it was used in the management of anxiety and in the treatment of muscle spasms until being discontinued worldwide by its manufacturer in 1996, due to rare but serious cutaneous reactions. It has a role as an anxiolytic drug, a muscle relaxant and an antipsychotic agent. It is a 1,3-thiazine, a lactam, a sulfone and a member of monochlorobenzenes.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov