Phentolamine Mesylate
商品编号：
TS0825
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详细介绍
l 基本信息 |
产品名称 | Phentolamine Mesylate(甲磺酸酚妥拉明) |
一般描述 | Phentolamine Mesylate is a reversible and nive alpha-adrenergic receptor antagonist, used for the prevention or control of hypertensive episodes. |
别 称 | 3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 65-28-1 |
分子式 | C18H23N3O4S | 分子量 | 377.459 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 白色至类白色粉末 |
溶解性(25°C) | DMSO | ≥50mg/mL |
乙醇 | ≥50mg/mL |
水 | ≥50mg/mL |
l 生物学信息 |
生物活性/药理作用 | Phentolamine Mesylate is the mesylate salt of a synthetic imidazoline with alpha-adrenergic antagonist activity. As a competitive alpha-adrenergic antagonist, phentolamine binds to alpha-1 and alpha-2 receptors, resulting in a decrease in peripheral vascular resistance and vasodilatation. This agent also may block 5-hydroxytryptamine (5-HT) receptors and stimulate release of histamine from mast cells. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
