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Trimebutine

商品编号: TS0847
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详细介绍

l  基本信息

产品名称

Trimebutine(曲美布汀)

一般描述

Trimebutine is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain.

别 称

Mebutin; [2-(dimethylamino)-2-phenylbutyl] 3,4,5-trimethoxybenzoate

纯 度

≥98.0%(HPLC)

CAS NO.

39133-31-8

分子式

C22H29NO5

分子量

387.476

适用范围

生物试剂,适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25°C)

DMSO

≥45mg/mL

乙醇

Insoluble

Insoluble

l  生物学信息

生物活性/药理作用

Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI disorders. It is used to restore normal bowel function and is commonly present in pharmaceutical mixtures as trimebutine maleate salt form. Trimebutine is not a FDA-approved drug, but it is available in Canada and several other international countries.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov