产品名称

Hypoxanthine(次黄嘌呤)

一般描述

Hypoxanthine, a naturally occurring purine derivative, an intermediate product of uric acid synthesis, formed from adenylic acid and itself a precursor of xanthine.

别 称

1,7-dihydropurin-6-one

纯 度

≥98.0%(HPLC)

CAS NO.

68-94-0

分子式

C⁵H⁴N⁴O

分子量

136.114

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至类白色固体

溶解性(25°C)

DMSO

Very slightly soluble

乙醇

Insoluble

水

Insoluble

l  生物学信息

生物活性/药理作用

Hypoxanthine is a purine-based organic compound in human muscle tissues, Hypoxanthine is formed during purine catabolism as a product of xanthine oxidase action on xanthine, and occasionally is found as a constituent of nucleic acids. The potent anti-inflammatory and cytoprotective effects of purines may be mediated by cell surface adenosine receptors. Hypoxanthine protects against oxidant-induced cell injury by inhibiting activation of nuclear poly(ADP-ribose) polymerase (PARP).

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov