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详细介绍
l 基本信息 |
产品名称 | Famciclovir(泛昔洛韦) |
一般描述 | Famciclovir is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections. |
别 称 | BRL-42810; [2-(acetyloxymethyl)-4-(2-aminopurin-9-yl)butyl] acetate |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 104227-87-4 |
分子式 | C14H19N5O4 | 分子量 | 321.337 |
适用范围 | 生物试剂,适用于细胞培养等 |
l 理化信息 |
外 观 | 固体 |
溶解性(25°C) | DMSO | ≥50mg/mL |
乙醇 | ≥35mg/mL |
水 | ≥50mg/mL |
l 生物学信息 |
生物活性/药理作用 | Famciclovir is a diacetyl 6-deoxy prodrug analog of the antiviral agent penciclovir. Orally administered, famciclovir in vivo is converted to penciclovir triphosphate, which is active against the Herpes viruses, including herpes simplex 1 and 2 and varicella-zoster. This agent inhibits the replication of viral DNA by interfering competitively with DNA polymerase. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |