产品名称

Mycophenolic acid(霉酚酸)

一般描述

Mycophenolic acid is a potent IMPDH inhibitor and the active metabolite of an immunosuppressive drug, used to prevent rejection in organ transplantation.

别 称

Mycophenolate; RS-61443

纯 度

≥98.0%(HPLC)

CAS NO.

24280-93-1

分子式

C¹⁷H²⁰O⁶

分子量

320.341

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至白色带黄色的固体

溶解性(25°C)

DMSO

≥50mg/mL

乙醇

~5mg/mL

水

Insoluble

l  生物学信息

生物活性/药理作用

Mycophenolic Acid is an antineoplastic antibiotic derived from various Penicillium fungal species. Mycophenolic acid is an active metabolite of the prodrug mycophenolate mofetil. Mycophenolic acid inhibits inosine monophosphate dehydrogenase (IMPDH), preventing the formation of guanosine monophosphate and synthesis of lymphocyte DNA that results in inhibition of lymphocyte proliferation, antibody production, cellular adhesion, and migration of T and B lymphocytes. Mycophenolic acid also has antibacterial, antifungal, and antiviral activities.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov