Amikacin hydrate
商品编号：
TS1275
备注：
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详细介绍
l 基本信息 |
产品名称 | Amikacin hydrate(阿米卡星) |
一般描述 | Amikacin hydrate is an aminoglycoside antibiotic used to treat different types of bacterial infections. |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 37517-28-5 |
分子式 | C22H43N5O13 | 分子量 | 585.6 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 白色至类白色固体 |
溶解性(25°C) | DMSO | Insoluble |
乙醇 | Insoluble |
水 | ≥50mg/mL |
l 生物学信息 |
生物活性/药理作用 | Amikacin is a broad-spectrum semi-synthetic aminoglycoside antibiotic, derived from kanamycin with antimicrobial property. Amikacin irreversibly binds to the bacterial 30S ribosomal subunit, specifically locking 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex and misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. This agent is usually used in short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
