产品名称

Trimethoprim(甲氧苄啶)

一般描述

Trimethoprim is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.

别 称

BW 56-72; NIH 204; NSC-106568; 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine

纯 度

≥98.0%(HPLC)

CAS NO.

738-70-5

分子式

C¹⁴H¹⁸N⁴O³

分子量

290.323

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至类白色固体

溶解性(25°C)

DMSO

≥45mg/mL

乙醇

Insoluble

水

Insoluble

l  生物学信息

生物活性/药理作用

Trimethoprim is a synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid. The antibacterial activity of this agent is potentiated by sulfonamides.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov