产品名称

Articaine HCl(阿替卡因盐酸盐)

一般描述

Articaine HCl is a dental local anesthetic which contains an additional ester group that is metabolized by estearases in blood and tissue.

别 称

Ultracaine; methyl 4-methyl-3-[2-(propylamino)propanoylamino]thiophene-2-carboxylate; hydrochloride

纯 度

≥98.0%(HPLC)

CAS NO.

23964-57-0

分子式

C¹³H²¹ClN²O³S

分子量

320.832

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至类白色固体

溶解性(25°C)

DMSO

≥50mg/mL

乙醇

≥50mg/mL

水

≥50mg/mL

l  生物学信息

生物活性/药理作用

Articaine Hydrochloride is the hydrochloride salt form of articaine, an amide-type local anesthetic. Articaine hydrochloride reversibly blocks nerve impulse conduction by binding to specific membrane sodium ion channels thereby interfering with the electrical excitation in the nerve, slowing the propagation of the nerve impulse and reducing the rate of rise of the action potential. This results in a loss of sensation at the injection site. Articaine hydrochloride is used for relief of pain in minor operations, usually in combination with the vasoconstrictor epinephrine.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov