产品名称

N-Ethylmaleimide

一般描述

N-Ethylmaleimide is an organic compound that is derived from maleic acid. It is an irreversible inhibitor of all cysteine peptidases, with alkylation occurring at the active site thiol group. 

别 称

1-ethylpyrrole-2,5-dione; NEM

纯 度

≥98.0%(HPLC)

CAS NO.

128-53-0

分子式

C⁶H⁷NO²

分子量

125.127

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至类白色固体

溶解性(25°C)

DMSO

≥15mg/mL

乙醇

≥15mg/mL

水

≥15mg/mL

l  生物学信息

生物活性/药理作用

N-ethylmaleimide is a member of the class of maleimides that is the N-ethyl derivative of maleimide. It has a role as an EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor, an EC 2.7.1.1 (hexokinase) inhibitor and an EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor. It derives from a maleimide.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov