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Travoprost

商品编号: TS1440
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详细介绍

l  基本信息

产品名称

Travoprost

一般描述

Travoprost is a PGF2a analog that was launched as an ophthalmic solution administered topically for the treatment of elevated intraocular hypertension as a result of open-angle glaucoma, a common optic neuropathy, and a leading cause of blindness. It can act as an agonist of prostaglandin F receptor.

别 称

Travoprostum

纯 度

≥98.0%(HPLC)

CAS NO.

157283-68-6

分子式

C26H35F3O6

分子量

500.555

适用范围

生物试剂,适用于细胞培养等

l  理化信息

外 观

无色至淡黄色油状物

l  生物学信息

生物活性/药理作用

Travoprost is a synthetic lipophilic isopropyl ester prodrug of the active compound travoprost free acid, a prostaglandin F2alpha analog with anti-glaucoma property. Upon administration, travoprost is hydrolysed to a free acid by corneal esterases, and then selectively stimulating the prostaglandin F (FP prostanoid) receptor, thereby increasing the uveoscleral outflow which leads to a reduction in intra-ocular pressure.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov