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详细介绍
l 基本信息 |
产品名称 | Travoprost |
一般描述 | Travoprost is a PGF2a analog that was launched as an ophthalmic solution administered topically for the treatment of elevated intraocular hypertension as a result of open-angle glaucoma, a common optic neuropathy, and a leading cause of blindness. It can act as an agonist of prostaglandin F receptor. |
别 称 | Travoprostum |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 157283-68-6 |
分子式 | C26H35F3O6 | 分子量 | 500.555 |
适用范围 | 生物试剂,适用于细胞培养等 |
l 理化信息 |
外 观 | 无色至淡黄色油状物 |
l 生物学信息 |
生物活性/药理作用 | Travoprost is a synthetic lipophilic isopropyl ester prodrug of the active compound travoprost free acid, a prostaglandin F2alpha analog with anti-glaucoma property. Upon administration, travoprost is hydrolysed to a free acid by corneal esterases, and then selectively stimulating the prostaglandin F (FP prostanoid) receptor, thereby increasing the uveoscleral outflow which leads to a reduction in intra-ocular pressure. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |