产品名称

Valproic acid(丙戊酸)

一般描述

Valproic acid is a fatty acid with anticonvulsant properties used in the treatment of epilepsy. It is also a histone deacetylase inhibitor and is under investigation for treatment of HIV and various cancers.

别 称

2-Propylvaleric Acid, Sodium valproate, 2-propylpentanoic acid

纯 度

≥99.0%(GC)

CAS NO.

99-66-1

分子式

C⁸H¹⁶O²

分子量

144.214

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

液体

l  生物学信息

生物活性/药理作用

Valproic Acid is a synthetic derivative of propylpentanoic acid with antiepileptic properties and potential antineoplastic and antiangiogenesis activities. In epilepsy, valproic acid appears to act by increasing the concentration of gamma-aminobutyric acid (GABA) in the brain. This agent's antitumor and antiangiogenesis activities may be related to the inhibition of histone deacetylases and nitric oxide synthase, which results in the inhibition of nitric oxide synthesis.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov