Pentamidine isethionate
商品编号：
TS1688
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详细介绍
l 基本信息 |
产品名称 | Pentamidine isethionate |
一般描述 | Pentamidine isethionate is an inhibitor of PRL Phosphatases and also inhibits synthesis of DNA, RNA and protein. |
别 称 | 4-[5-(4-carbamimidoylphenoxy)pentoxy]benzenecarboximidamide; 2-hydroxyethanesulfonic acid |
纯 度 | ≥99.0%(HPLC) | CAS NO. | 140-64-7 |
分子式 | C23H36N4O10S2 | 分子量 | 592.679 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 固体 |
溶解性(25°C) | DMSO | ≥50mg/mL |
乙醇 | Insoluble |
水 | ≥50mg/mL |
l 生物学信息 |
生物活性/药理作用 | Pentamidine Isethionate is a synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent that appears to interact with the minor groove of AT-rich DNA regions of the pathogen genome, interfering with DNA replication and function. It is effective in the treatment of trypanosomiasis, leishmaniasis, some fungal infections, and Pneumocystis carinii pneumonia in HIV-infected patients. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
