产品名称

Hexamethonium Dibromide

一般描述

Hexamethonium Dibromide is a selective antagonist of neuronal-type nicotinic AChR in ganglia.

别 称

trimethyl-[6-(trimethylazaniumyl)hexyl]azanium; dibromide

纯 度

≥99.0%(HPLC)

CAS NO.

55-97-0

分子式

C¹²H³⁰Br²N²

分子量

362.194

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25°C)

DMSO

Insoluble

乙醇

Insoluble

水

≥45mg/ml

l  生物学信息

生物活性/药理作用

A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov