Loxapine Succinate
商品编号：
TS1749
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详细介绍
l 基本信息 |
产品名称 | Loxapine Succinate |
一般描述 | Loxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent. |
别 称 | butanedioic acid; 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine |
纯 度 | ≥99.0%(HPLC) | CAS NO. | 27833-64-3 |
分子式 | C22H24ClN3O5 | 分子量 | 445.9 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 白色至类白色固体 |
溶解性(25°C) | DMSO | ≥45mg/ml |
乙醇 | Very slightly soluble |
水 | Insoluble |
l 生物学信息 |
生物活性/药理作用 | Loxapine Succinate is the succinate salt form of loxapine, a tricyclic dibenzoxazepine antipsychotic agent with antiemetic, sedative, anticholinergic, and antiadrenergic actions. Loxapine succinate exerts its
actions by blocking the dopamine receptors at postsynaptic receptor sites in the limbic system, cortical system and basal ganglia, thereby reducing the hallucinations and delusions that are associated with schizophrenia. This agent also exerts extrapyramidal side effects. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
