产品名称

Clorprenaline HCl(盐酸氯丙那林)

一般描述

Clorprenaline HCl is a β2-receptor agonist, it has a significant expansion of the bronchial effect.

别 称

NSC 334693; 1-(2-chlorophenyl)-2-(propan-2-ylamino)ethanol; hydrochloride

纯 度

≥99.0%(HPLC)

CAS NO.

6933-90-0

分子式

C¹¹H¹⁷Cl²NO

分子量

250.163

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25°C)

DMSO

≥45mg/ml

乙醇

≥45mg/ml

水

≥45mg/ml

l  生物学信息

生物活性/药理作用

Clorprenaline Hydrochloride is the hydrochloride salt form of clorprenaline, a beta-2 adrenergic agonist with bronchodilator activity. Clorprenaline selectively binds to and activates beta-2 adrenergic receptors in bronchiolar smooth muscle, thereby causing stimulation of adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased intracellular cAMP levels cause relaxation of bronchial smooth muscle. This increases air flow and prevents bronchospasms and may eventually lead to an improvement of airway function.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov