产品名称

Mezlocillin Sodium(美洛西林钠)

一般描述

Mezlocillin sodium is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive,organisms.

别 称

sodium; (2S,5R,6R)-3,3-dimethyl-6-[[(2R)-2-[(3-methylsulfonyl-2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

纯 度

≥99.0%(HPLC)

CAS NO.

42057-22-7

分子式

C²¹H24N⁵NaO⁸S²

分子量

561.56

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至类白色固体

溶解性(25°C)

DMSO

≥50mg/ml

乙醇

Insoluble

水

≥50mg/ml

l  生物学信息

生物活性/药理作用

Mezlocillin Sodium Monohydrate is the monohydrate and sodium salt form of mezlocillin, a broad-spectrum, semisynthetic ampicillin-derived acylureidopenicillin with antibacterial activity. Mezlocillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.Inactivation of PBPs interferes with the cross-age of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov