产品名称

Liothyronine Sodium(碘塞罗宁钠)

一般描述

Liothyronine Sodium is the most potent form of thyroid hormone acting on the body to increase the basal metabolic rate, affect protein synthesis.

别 称

sodium; (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate

纯 度

≥95.0%(HPLC)

CAS NO.

55-06-1

分子式

C¹⁵H¹¹I³NNaO⁴

分子量

672.959

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至浅棕色固体

溶解性(25°C)

DMSO

≥50mg/ml

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4).

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov