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Pilocarpine HCl

商品编号: TS1845
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详细介绍

l  基本信息

产品名称

Pilocarpine HCl(盐酸毛果芸香碱)

一般描述

Pilocarpine HCl is a nive muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy.

别 称

NSC 5746 HCl; (3S,4R)-3-ethyl-4-[(3-methylimidazol-4-yl)methyl]oxolan-2-one; hydrochloride

纯 度

≥98.0%(HPLC)

CAS NO.

54-71-7

分子式

C11H17ClN2O2

分子量

244.719

适用范围

生物试剂,适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25°C)

DMSO

≥35mg/ml

≥35mg/ml

l  生物学信息

生物活性/药理作用

Pilocarpine Hydrochloride is the hydrochloride salt of a natural alkaloid extracted from plants of the genus Pilocarpus with cholinergic agonist activity. As a cholinergic parasympathomimetic agent, pilocarpine predominantly binds to muscarinic receptors, thereby inducing exocrine gland secretion and stimulating smooth muscle in the bronchi, urinary tract, biliary tract, and intestinal tract. When applied topically to the eye, this agent stimulates the sphincter pupillae to contract, resulting in miosis; stimulates the ciliary muscle to contract, resulting in spasm of accomodation; and may cause a transitory rise in intraocular pressure followed by a more persistent fall due to opening of the trabecular meshwork and an increase in the outflow of aqueous humor.

应 用

1.Miotics

2.Muscarinic Agonists

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov