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详细介绍
l 基本信息 |
产品名称 | Diacerein(双醋瑞因) |
一般描述 | Diacerein is an inhibitor of pro-inflammatory cytokine Interleukin-1B(IL-1B) production, prescribed for osteoarthritis and chronic inflammatory arthritis. |
别 称 | 4,5-diacetyloxy-9,10-dioxoanthracene-2-carboxylic acid |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 13739-02-1 |
分子式 | C19H12O8 | 分子量 | 368.297 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 黄色固体 |
溶解性(25°C) | DMSO | ≥35mg/ml |
水 | Very slightly soluble |
l 生物学信息 |
生物活性/药理作用 | Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including sevre diarrhea [L780]. Diacerein is under investigation for the treatment of Insulin Resistance, Diabetes Mellitus (Type 2), and
Diabetes-Related Complications. |
应 用 | Anti-Inflammatory Agents |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
