产品名称

Mupirocin(莫匹罗星)

一般描述

Mupirocin is an isoleucyl t-RNA synthetase inhibitor, used in the treatment of bacterial skin infections. 

别 称

9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl]oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid

纯 度

≥97.0%(HPLC)

CAS NO.

12650-69-0

分子式

C²⁶H⁴⁴O⁹

分子量

500.629

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至褐色固体

溶解性(25°C)

DMSO

≥50mg/ml

水

≥35mg/ml

l  生物学信息

生物活性/药理作用

Mupirocin is a natural crotonic acid derivative extracted from Pseudomonas fluorescens. Mupirocin inhibits bacterial protein synthesis by specific reversible binding to bacterial  isoleucyl tRNA synthase. With excellent activity against gram-positive  staphylococci and streptococci, it is primarily used for treatment of primary and secondary skin disorders, nasal infections, and wound healing.

应 用

1.Anti-Bacterial Agents

2.Protein Synthesis Inhibitors

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov