产品名称

Mefloquine HCl(盐酸甲氟喹)

一般描述

Mefloquine HCl is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug. 

别 称

(S)-[2,8-bis(trifluoromethyl)quinolin-4-yl]-[(2R)-piperidin-2-yl]methanol; hydrochloride

纯 度

≥98.0%(HPLC)

CAS NO.

51773-92-3

分子式

C¹⁷H¹⁷ClF⁶N²O

分子量

414.776

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至类白色固体

溶解性(25°C)

DMSO

≥50mg/ml

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Mefloquine Hydrochloride is the hydrochloride salt form of mefloquine, a piperidinyl quinidine with antimalarial activity. Although the exact mechanism of mefloquine hydrochloride is largely unknown, this agent acts as a blood schizonticide and probably exert its actions by interacting with the phospholipid b, thereby interfering with the stability of the cell membrane and causing cell lysis. Mefloquine hydrochloride is active against Plasmodium falciparum and Plasmodium vivax.

应 用

Antimalarials

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov