产品名称

Dithranol(地蒽酚)

一般描述

Dithranol is one of the most important local therapeutic agents against the common skin disease, psoriasis.

别 称

Anthralin; cignoline; 1,8,9-trihydroxyanthracene; 1,8-dihydroxy-10H-anthracen-9-one

纯 度

≥97.0%(HPLC)

CAS NO.

1143-38-0

分子式

C¹⁴H¹⁰O³

分子量

226.23

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25°C)

DMSO

Slightly soluble

l  生物学信息

生物活性/药理作用

Anthralin is a natural anthraquinone derivative, anti-psoriatic and anti-inflammatory Anthralin (dithranol) controls skin growth by reducing DNA synthesis and mitotic activity in the hyperplastic epidermis, restoring a normal rate of cell proliferation and keratinization. Used topically in the treatment of psoriasis, dermatoses, and alopecia areata, it is also used in biomedical research due to its effect on EGFR autophosphorylation.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov