产品名称

Fenoldopam mesylate(甲磺酸非诺多泮)

一般描述

Fenoldopam mesylate is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.

别 称

SKF 82526 (mesylate), Fenoldopam methanesulfonate, Corlopam mesylate

纯 度

≥98.0%(HPLC)

CAS NO.

67227-57-0

分子式

C¹⁷H²⁰ClNO⁶S

分子量

401.86

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至褐色固体

溶解性(25°C)

DMSO

≥45mg/ml

乙醇

Insoluble

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Fenoldopam Mesylate is the mesylate salt form of fenoldopam, a benzazepine derivative with rapid-acting vasodilator activity. Fenoldopam mesylate is a racemic mixture of S- and R- isomers; the latter is responsible for the biological activity and has a significantly higher affinity for dopamine  D1-like receptors (D1 and D5) as well as moderate affinity to alpha-2 adrenergic receptors. This agent selectively activates the dopamine D1-like  receptor, thereby causing vasodilatation and increasing renal perfusion.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov