产品名称

Hexachlorophene(六氯酚)

一般描述

Hexachlorophene is a potent KCNQ1/KCNE1 potassium channel activator with EC50 of 4.61 ± 1.29 μM It can also attenuate Wnt/beta-catenin signaling through the Siah-1-mediated beta-catenin degradation.

别 称

Hexachlorofen, Fostril, Nabac, pHisoHex; 3,4,6-trichloro-2-[(2,3,5-trichloro-6-hydroxyphenyl)methyl]phenol

纯 度

≥99.0%(HPLC)

CAS NO.

70-30-4

分子式

C¹³H⁶Cl⁶O²

分子量

406.9

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25°C)

DMSO

≥45mg/ml

乙醇

≥45mg/ml

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Hexachlorophene is a chlorinated bisphenol antiseptic agent with bacteriostatic activity. Hexachlorophene is used topically in soaps, creams and dermatological preparations and is active against gram-positive organisms, but much less effective against gram-negative organisms.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov