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详细介绍
l 基本信息 |
产品名称 | Lesinurad |
一般描述 | Lesinurad is a selective uric acid reabsorption inhibitor (SURI) under investigation for treatment of gout in combination with xanthine oxidase inhibitors. |
别 称 | RDEA 594; 2-[[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-1,2,4-triazol-3-yl]sulfanyl]acetic acid |
纯 度 | ≥99.0%(HPLC) | CAS NO. | 878672-00-5 |
分子式 | C17H14BrN3O2S | 分子量 | 404.28 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 白色至米白色固体 |
溶解性(25°C) | DMSO | ≥45mg/ml |
乙醇 | ≥35mg/ml |
水 | Very slightly soluble |
l 生物学信息 |
生物活性/药理作用 | Lesinurad is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had limited clinical use, but has not been associated with serum enzyme elevations during therapy or with instances of clinically apparent liver injury. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
