产品名称

Procaine(普鲁卡因)

一般描述

Procaine is a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses.

别 称

Procaine, Novocaine, Duracaine, Spinocaine, 2-(diethylamino)ethyl 4-aminobenzoate

纯 度

≥99.0%(HPLC)

CAS NO.

59-46-1

分子式

C¹³H²⁰N²O²

分子量

236.31

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25°C)

DMSO

≥25mg/ml

乙醇

≥25mg/ml

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Procaine is a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov