Alosetron Hydrochloride
商品编号:
TS2091
备注:
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详细介绍
l 基本信息 |
产品名称 | Alosetron Hydrochloride(盐酸阿洛司琼) |
一般描述 | Alosetron Hydrochloride is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. |
别 称 | GR 68755C, GR 68755, GR 68755X, Lotronex |
纯 度 | ≥99.0%(HPLC) | CAS NO. | 122852-69-1 |
分子式 | C17H19ClN4O | 分子量 | 330.81 |
适用范围 | 生物试剂,适用于细胞培养等 |
l 理化信息 |
外 观 | 白色至米色粉末 |
溶解性(25°C) | DMSO | Very slightly soluble |
乙醇 | Insoluble |
水 | Very slightly soluble |
l 生物学信息 |
生物活性/药理作用 | Alosetron Hydrochloride is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system, particularly on enteric and nociceptive sensory neurons, thereby affecting the regulation of visceral pain, decreasing gastrointestinal contraction and motility, and decreasing gastrointestinal secretions. This agent is used to treat diarrhea-predominant irritable bowel syndrome in women. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |