产品名称

Cefazedone(头孢西酮)

一般描述

Cefazedone is a semisynthetic first-generation cephalosporin with antibacterial activity.

别 称

Refosporen, Cefazedonum

纯 度

≥99.0%(HPLC)

CAS NO.

56187-47-4

分子式

C¹⁸H¹⁵Cl²N⁵O⁵S³

分子量

548.44

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25°C)

DMSO

≥45mg/ml

l  生物学信息

生物活性/药理作用

Cefazedone is a semisynthetic first-generation cephalosporin with antibacterial activity. Cefazedone binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-age of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov